9/08/2008

The active ingredient in chocolate can cough

An ingredient in chocolate could be used to stop persistent coughs and lead to more effective medicines, researchers say. The study found that theobromine, found in cocoa, was nearly a third more effective in stopping persistent coughs than codeine, currently considered the best cough medicine.

The researchers, from Imperial College London (ICL), said the discovery could lead to more effective cough treatments. Ten healthy volunteers were either given theobromine, codeine or a dummy pill during the trial, which also involved Royal Brompton Hospital and St Bartholomew's Hospital.
The researchers, writing in the online FASEB Journal, said that theobromine worked by suppressing vagus nerve activity, which is responsible for causing coughing. They also found that unlike standard cough treatments, theobromine caused no adverse effects on the cardiovascular or central nervous systems, such as drowsiness.

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